Cleveland Browns vs. Steelers: 4 match-ups to watch

Oct 12, 2014; Cleveland, OH, USA; Cleveland Browns defensive end John Hughes (93) sacks Pittsburgh Steelers quarterback Ben Roethlisberger (7) during the third quarter at FirstEnergy Stadium. Mandatory Credit: Andrew Weber-USA TODAY Sports

The Cleveland Browns head to Pittsburgh on Sunday looking to defeat the Pittsburgh Steelers at Heinz Field for the first time since 2003.

The Browns, who enter having lost four consecutive games, have major question marks. While head coach Mike Pettine would not announce the starting quarterback for the game, it is expected that Johnny Manziel will make his second straight start.

Related: Browns vs. Steelers: 5 Questions with Still Curtain

One plus for the Browns is that Pittsburgh quarterback Ben Roethlisberger is expected to be out with a foot injury, with Landry Jones expected to get the start for Pittsburgh. The Browns defense must be aggressive and pressure Jones.

Offensively, if Manziel starts, he needs to continue to improve and do a better job playing in the context of the offense.

The Browns are desperate to get a win in a hostile environment and enter the bye week on a positive note. To make that happen, these key match-ups will be deciding factors.

Next: Johnny Manziel vs. Pittsburgh defense